Patel, Rajiv Kumar, Gurpreet Singh Gulati 1, Neeraj Parakh 2, Sandeep Seth 2, Randeep Guleria 3, C. OP2: Role of 68Ga-DOTANOC positron emission tomography/computed tomography and myocardial perfusion imaging in cardiac sarcoidosis: A comparison to cardiac magnetic resonance Conclusion: Our findings indicate that asymptomatic diabetic patients have significant dyssynchrony compared to normal healthy nondiabetic controls and dyssynchrony on phase analysis with cardiac PET can be used to predict diabetic cardiomyopathy. Mean PSD and mean HBW of stress study were also significantly higher in patients with asymptomatic diabetes compared to normal nondiabetic controls (PSD = 25.2 vs. Results: The mean PSD and HBW of resting study were significantly higher in diabetic patients compared to nondiabetic healthy controls (PSD = 28 vs. The statistical significance of the dyssynchrony parameters (PSD and HBW) in asymptomatic diabetics versus normal healthy controls was assessed using the Mann–Whitney test. Phase standard deviation (PSD) and histogram bandwidth (HBW) were recorded from phase histogram in both rest and stress PET images in all the patients included in our study. LV dyssynchrony assessment was done using phase analysis with Corridor 4DM software. Twenty-eight patients (12 males, 16 females) aged 39–72 years with the absence of diabetes, obesity, and low risk for coronary artery disease who underwent N-13 labeled NH3 cardiac PET were taken as controls. Among them, 33 patients aged 40–70 years (21 males, 12 females) with asymptomatic type II diabetes, absence of obesity, and other comorbidities underwent N-13-labeled NH3 cardiac PET. Materials and Methods: We retrospectively analyzed 124 patients aged 30–78 years who underwent 1 day stress/rest N-13 labeled NH3 cardiac PET from December 2015 to July 2018. This study aims to evaluate LV mechanical dyssynchrony with N-13 labeled NH3 positron emission tomography (PET) in asymptomatic diabetic patients (>3 years) compared to age-matched healthy controls.
Recently, there is emerging evidence to assess the role of dyssynchrony in identifying asymptomatic diabetic patients who may develop diabetic cardiomyopathy. The role of LV mechanical dyssynchrony assessment with gated single-photon emission computed tomography in selection and response assessment of patients, who undergo cardiac resynchronization therapy, is widely discussed. Vankadari Kousik, Ashwani Sood, Anish Bhattacharya, Bhagwant Rai Mittalĭepartment of Nuclear Medicine, PGIMER, Chandigarh, Indiaīackground and Objectives: Dyssynchrony refers to abnormal myocardial activation leading to inhomogenous contraction of the left ventricular (LV) muscle fibers and reduced LV ejection fraction.
OP1: Dyssynchrony evaluation using NH3 cardiac positron emission tomography in asymptomatic diabetic patients compared to age-matched healthy controls with low risk of coronary artery disease
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